Promising synthetic derivatives of macrolactone natural product (-)-A26771B have been designed and synthesized both from semisynthesis and total synthesis. Further optimization led to the first synthesis of macrolactam analogs of (-)-A26771B with improved antibacterial activity and metabolic stability.

More Resources & Publications

{"acf_fc_layout":"postList","postList_model":{"ID":3651,"post_author":"5","post_date":"2023-09-05 09:18:27","post_date_gmt":"2023-09-05 07:18:27","post_content":"","post_title":"More news","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"more-news","to_ping":"","pinged":"","post_modified":"2023-11-20 08:54:07","post_modified_gmt":"2023-11-20 07:54:07","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.edelris.com\/?post_type=waz_post_template&p=3651","menu_order":38,"post_type":"waz_post_template","post_mime_type":"","comment_count":"0","filter":"raw"},"postList_post_type":"post","postList_category_post":[{"term_id":43,"name":"Publication","slug":"publication","term_group":0,"term_taxonomy_id":43,"taxonomy":"category","description":"","parent":0,"count":52,"filter":"raw","term_order":"9"},{"term_id":44,"name":"Document","slug":"document","term_group":0,"term_taxonomy_id":44,"taxonomy":"category","description":"","parent":0,"count":1,"filter":"raw","term_order":"10"},{"term_id":45,"name":"Video","slug":"video","term_group":0,"term_taxonomy_id":45,"taxonomy":"category","description":"","parent":0,"count":0,"filter":"raw","term_order":"11"}],"postList_category_actualites":false,"postList_nb_item_per_line":"postList_2_item","postList_nb_max_item":"2","postList_order_by":"none","postList_order_date_which":"acf","postList_order_date_elements":"future","postList_order_date_ordering":"ASC","postList_set_link":true,"postList_link_waz_popup":true,"postList_category_navigation":false,"postList_rub_nav_dropdown":false,"postList_rub_nav_position":"left","postList_rub_nav_all":"Tous les articles","postList_pagination":false,"postList_pagination_nb_posts":12,"postList_pagination_btn_model":false,"postList_pagination_text":"","options":{"animation":false,"animation_delay":0,"animation_element_delay":100,"margin_bottom":"","postList_id":""},"postList_limit_title":"","postList_limit_subtitle":"","postList_limit_description":"","postList_limit_break":"word","postList_limit_add_to_end":"","postList_use_custom_post_type":false,"postList_custom_post_type":"","postList_custom_taxonomy":"","postList_custom_toxonomy_values":"","postList_custom_title":"","postList_custom_subtitle":"","postList_custom_description":"","postList_custom_date":""}